The home side are currently fourth in the table, boasting seven points from their opening three matches, while Espanyol are down in 16th, having collected just one point from their first three games.
Athletic finished eighth in La Liga last season, boasting 55 points from their 38 matches, and they will be looking to secure a similar spot this term, with a top-seven challenge a possibility.
Ernesto Valverde‘s side have made a strong start to the 2022-23 campaign, picking up seven points from their opening three matches, which has left them in fourth position in the table.
Athletic opened their season with a goalless draw against Mallorca before recording a 1-0 victory over Valencia on August 21; the Basque side then put four unanswered goals past Cadiz on August 29 in a strong performance.
The Lions, who will also face Elche and Rayo Vallecano before the September international break, recorded a 2-1 win over Espanyol in the corresponding match last season, while they have not lost a La Liga game to the Catalan side since November 2018.
Espanyol, meanwhile, opened their 2022-23 La Liga campaign with a 2-2 draw against Celta Vigo, but they have lost their two games since, going down 2-0 at home to Rayo Vallecano and 3-1 to Real Madrid.
A total of one point from three matches has left Diego Martinez‘s side in 16th position in the table, only one point more than basement side Cadiz, and their form is a concern ahead of difficult games against Sevilla and Real Sociedad before the international break.
Espanyol were relegated from La Liga at the end of the 2019-20 campaign but returned to the top level at the first time of asking and managed to finish 14th in Spain’s top flight last term.
The Catalan side have been active during the summer market and managed to secure Martin Braithwaite‘s signature on transfer deadline day following his release from Barcelona.
Espanyol had the second-worst away record in Spain’s top flight last season, picking up just nine points from 19 matches, recording only one victory in the process.
Meanwhile, the ankle problem that Inaki Williams picked up against Cadiz will rule him out, so the forward’s run of appearing in 236 consecutive La Liga matches is set to come to an end against Espanyol.
Guruzeta, who scored a brace off the bench last time out, is expected to come into the starting side, with the 25-year-old likely to lead the line with support from Iker Muniain, Berenguer and Nico Williams.
Braithwaite is in line to make his debut for the Catalan club, but he is yet to play this season, so the experienced attacker is likely to be among the substitutes rather than in the first XI.
Athletic Bilbao possible starting lineup:
Simon; De Marcos, Vivian, Yeray, Lekue; Sancet, Vesga; N Williams, Muniain, Berenguer; Guruzeta
Espanyol possible starting lineup:
Garcia; Gil, Calero, Cabrera, Olivan; Sanchez, Edu, Bare, Darder, Puado; Joselu